{"id":1986,"date":"2017-09-01T11:30:52","date_gmt":"2017-09-01T14:30:52","guid":{"rendered":"http:\/\/atlanticpath.ca\/?p=1986"},"modified":"2020-08-04T14:15:26","modified_gmt":"2020-08-04T17:15:26","slug":"atopic-dermatitis-and-risk-of-hypertension-type-2-diabetes-myocardial-infarction-and-stroke-in-a-cross-sectional-analysis-from-the-canadian-partnership-for-tomorrow-project","status":"publish","type":"post","link":"https:\/\/www.atlanticpath.ca\/index.php\/2017\/09\/01\/atopic-dermatitis-and-risk-of-hypertension-type-2-diabetes-myocardial-infarction-and-stroke-in-a-cross-sectional-analysis-from-the-canadian-partnership-for-tomorrow-project\/","title":{"rendered":"Atopic dermatitis and risk of hypertension, type-2 diabetes, myocardial infarction and stroke in a cross-sectional analysis from the Canadian Partnership for Tomorrow Project."},"content":{"rendered":"

Atopic dermatitis and risk of hypertension, type-2 diabetes, myocardial infarction and stroke in a cross-sectional analysis from the Canadian Partnership for Tomorrow Project.<\/strong><\/p>\n

Authors:\u00a0<\/strong>Drucker, A.M., Qureshi, A.A., Dummer, T.J.B., Parker, L., Li, W.Q. (2017).<\/p>\n

Journal: \u00a0<\/strong>British Journal of Dermatology<\/em>. Doi: 10.1111\/bjd.15727.<\/p>\n

Abstract:\u00a0<\/strong>Atopic dermatitis (AD) has been associated with\u00a0cardiovascular\u00a0risk factors and diseases, but epidemiologic studies to date have found conflicting results.<\/p>\n

Objectives<\/strong>: We aimed to determine the associations of AD with hypertension, type-2 diabetes (T2D), myocardial infarction (MI) and stroke.<\/p>\n

Methods:<\/strong> We conducted a cross-sectional analysis of baseline data from the Canadian Partnership for Tomorrow Project which includes Canadian residents aged 30-74 living in British Columbia, Alberta, Ontario, Quebec and the\u00a0Atlantic\u00a0Provinces. We excluded participants with incomplete data on AD, hypertension, T2D, MI or stroke, who had type-1 or gestational diabetes or who developed any of the outcomes at an age prior to a diagnosis of AD, leaving 259,119 participants in our analysis. We used logistic regression to calculate age and sex- and multivariable-adjusted odds ratios (OR) and 95% confidence intervals (CI) between AD and subsequent hypertension, T2D, MI and stroke.<\/p>\n

Results<\/strong>: AD was reported by 21,379 (8.4%) participants. A total of 52,787 cases of hypertension, 12,739 cases of T2D, 4,390 cases of MI and 2,235 cases of stroke were reported by participants at enrollment. In the multivariable-adjusted model, AD was associated with decreased odds (OR, 95% CI) of hypertension (0.87, 0.83-0.90), T2D (0.78, 0.71-0.84), MI (0.87, 0.75-1.00) and stroke (0.79, 0.66-0.95).<\/p>\n

Conclusions<\/strong>: We did not find evidence of a positive association between AD and subsequent hypertension, T2D, MI or stroke; AD was inversely associated with these outcomes in our\u00a0study. Given our findings and the conflicting literature, AD is likely not a major risk factor for\u00a0cardiovascular\u00a0disease.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Atopic dermatitis and risk of hypertension, type-2 diabetes, myocardial infarction and stroke in a cross-sectional analysis from the Canadian Partnership for Tomorrow Project. Authors:\u00a0Drucker, A.M., Qureshi, A.A., Dummer, T.J.B., Parker, L., Li, W.Q. (2017). Journal: \u00a0British Journal of Dermatology. Doi: 10.1111\/bjd.15727. Abstract:\u00a0Atopic dermatitis (AD) has been associated with\u00a0cardiovascular\u00a0risk factors and diseases, but epidemiologic studies to date have found conflicting results. Objectives: We aimed to determine the associations of AD with hypertension, type-2 diabetes (T2D), myocardial infarction (MI) and stroke. Methods: We conducted a cross-sectional analysis of baseline data from the Canadian Partnership for Tomorrow Project which includes Canadian residents aged 30-74 living in British Columbia, Alberta, Ontario, Quebec and the\u00a0Atlantic\u00a0Provinces. We excluded participants with incomplete data on AD, hypertension, T2D, MI or stroke, who had type-1 or gestational diabetes or who developed any of the outcomes at an age prior to a diagnosis of AD, leaving 259,119 participants in our analysis. We used logistic regression to calculate age and sex- and multivariable-adjusted odds ratios (OR) and 95% confidence intervals (CI) between AD and subsequent hypertension, T2D, MI and stroke. Results: AD was reported by 21,379 (8.4%) participants. A total of 52,787 cases of hypertension, 12,739 cases of T2D, 4,390 cases of MI and 2,235 cases of stroke were reported by participants at enrollment. In the multivariable-adjusted model, AD was associated with decreased odds (OR, 95% CI) of hypertension (0.87, 0.83-0.90), T2D (0.78, 0.71-0.84), MI (0.87, 0.75-1.00) and stroke (0.79, 0.66-0.95). Conclusions: We did not find evidence of a positive association between AD and subsequent hypertension, T2D, MI or stroke; AD was inversely associated with these outcomes in our\u00a0study. Given our findings and the conflicting literature, AD is likely not a major risk factor for\u00a0cardiovascular\u00a0disease.  <\/p>\n","protected":false},"author":1,"featured_media":1988,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_eb_attr":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":"","_wpscppro_dont_share_socialmedia":false,"_wpscppro_custom_social_share_image":0,"_facebook_share_type":"","_twitter_share_type":"","_linkedin_share_type":"","_pinterest_share_type":"","_linkedin_share_type_page":"","_instagram_share_type":"","_medium_share_type":"","_threads_share_type":"","_selected_social_profile":[],"_wpsp_enable_custom_social_template":false,"_wpsp_social_scheduling":{"enabled":false,"datetime":null,"platforms":[],"status":"template_only","dateOption":"today","timeOption":"now","customDays":"","customHours":"","customDate":"","customTime":"","schedulingType":"absolute"},"_wpsp_active_default_template":true},"categories":[4],"tags":[],"class_list":["post-1986","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publications"],"acf":[],"modified_by":"pathwp","_links":{"self":[{"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/posts\/1986","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/comments?post=1986"}],"version-history":[{"count":2,"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/posts\/1986\/revisions"}],"predecessor-version":[{"id":2003,"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/posts\/1986\/revisions\/2003"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/media\/1988"}],"wp:attachment":[{"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/media?parent=1986"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/categories?post=1986"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/tags?post=1986"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}