{"id":2439,"date":"2019-06-19T07:30:13","date_gmt":"2019-06-19T11:30:13","guid":{"rendered":"http:\/\/www2.atlanticpath.ca\/?p=2439"},"modified":"2020-05-13T12:50:33","modified_gmt":"2020-05-13T16:50:33","slug":"the-canadian-partnership-for-tomorrow-project-a-pan-canadian-platform-for-research-on-chronic-disease-prevention","status":"publish","type":"post","link":"https:\/\/www.atlanticpath.ca\/index.php\/2019\/06\/19\/the-canadian-partnership-for-tomorrow-project-a-pan-canadian-platform-for-research-on-chronic-disease-prevention\/","title":{"rendered":"The Canadian Partnership for Tomorrow Project: a pan-Canadian platform for research on chronic disease prevention"},"content":{"rendered":"<p><strong>Authors<\/strong>: Trevor J.B. Dummer,\u00a0Philip Awadalla,\u00a0Catherine Boileau,\u00a0Camille Craig,\u00a0Isabel Fortier,\u00a0Vivek Goel,\u00a0Jason M.T. Hicks,\u00a0S\u00e9bastien Jacquemont,\u00a0Bartha Maria Knoppers,\u00a0Nhu Le,\u00a0Treena McDonald,\u00a0John McLaughlin,\u00a0Anne-Marie Mes-Masson,\u00a0Anne-Monique Nuyt,\u00a0Lyle J. Palmer,\u00a0Louise Parker,\u00a0Mark Purdue,\u00a0Paula J. Robson,\u00a0John J. Spinelli,\u00a0David Thompson,\u00a0Jennifer Vena,\u00a0Ma\u2019n Zawati\u00a0and\u00a0with the CPTP Regional Cohort Consortium<\/p>\n<p><strong>BACKGROUND<\/strong>:<\/p>\n<p>Understanding the complex interaction of risk factors that increase the likelihood of developing common diseases is challenging. The Canadian Partnership for Tomorrow Project (CPTP) is a prospective cohort study created as a population-health research platform for assessing the effect of genetics, behaviour, family health history and environment (among other factors) on chronic diseases. METHODS: Volunteer participants were recruited from the general Canadian population for a confederation of 5 regional cohorts. Participants were enrolled in the study and core information obtained using 2 approaches: attendance at a study assessment centre for all study measures (questionnaire, venous blood sample and physical measurements) or completion of the core questionnaire (online or paper), with later collection of other study measures where possible. Physical measurements included height, weight, percentage body fat and blood pressure. Participants consented to passive follow-up through linkage with administrative health databases and active follow-up through recontact. All participant data across the 5 regional cohorts were harmonized. RESULTS: A total of 307\u202f017 participants aged 30\u201374 from 8 provinces were recruited. More than half provided a venous blood sample and\/or other biological sample, and 33% completed physical measurements. A total of 709 harmonized variables were created; almost 25% are available for all participants and 60% for at least 220\u202f000 participants. INTERPRETATION: Primary recruitment for the CPTP is complete, and data and biosamples are available to Canadian and international researchers through a dataaccess process. The CPTP will support research into how modifiable risk factors, genetics and the environment interact to affect the development of cancer and other chronic diseases, ultimately contributing evidence to reduce the global burden of chronic disease.<\/p>\n<p><strong>Link<\/strong>:\u00a0<a href=\"https:\/\/doi.org\/10.1503\/cmaj.170292\"> https:\/\/doi.org\/10.1503\/cmaj.170292<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Authors: Trevor J.B. Dummer,\u00a0Philip Awadalla,\u00a0Catherine Boileau,\u00a0Camille Craig,\u00a0Isabel Fortier,\u00a0Vivek Goel,\u00a0Jason M.T. Hicks,\u00a0S\u00e9bastien Jacquemont,\u00a0Bartha Maria Knoppers,\u00a0Nhu Le,\u00a0Treena McDonald,\u00a0John McLaughlin,\u00a0Anne-Marie Mes-Masson,\u00a0Anne-Monique Nuyt,\u00a0Lyle J. Palmer,\u00a0Louise Parker,\u00a0Mark Purdue,\u00a0Paula J. Robson,\u00a0John J. Spinelli,\u00a0David Thompson,\u00a0Jennifer Vena,\u00a0Ma\u2019n Zawati\u00a0and\u00a0with the CPTP Regional Cohort Consortium BACKGROUND: Understanding the complex interaction of risk factors that increase the likelihood of developing common diseases is challenging. The Canadian Partnership for Tomorrow Project (CPTP) is a prospective cohort study created as a population-health research platform for assessing the effect of genetics, behaviour, family health history and environment (among other factors) on chronic diseases. METHODS: Volunteer participants were recruited from the general Canadian population for a confederation of 5 regional cohorts. Participants were enrolled in the study and core information obtained using 2 approaches: attendance at a study assessment centre for all study measures (questionnaire, venous blood sample and physical measurements) or completion of the core questionnaire (online or paper), with later collection of other study measures where possible. Physical measurements included height, weight, percentage body fat and blood pressure. Participants consented to passive follow-up through linkage with administrative health databases and active follow-up through recontact. All participant data across the 5 regional cohorts were harmonized. RESULTS: A total of 307\u202f017 participants aged 30\u201374 from 8 provinces were recruited. More than half provided a venous blood sample and\/or other biological sample, and 33% completed physical measurements. A total of 709 harmonized variables were created; almost 25% are available for all participants and 60% for at least 220\u202f000 participants. INTERPRETATION: Primary recruitment for the CPTP is complete, and data and biosamples are available to Canadian and international researchers through a dataaccess process. The CPTP will support research into how modifiable risk factors, genetics and the environment interact to affect the development of cancer and other chronic diseases, ultimately contributing evidence to reduce the global burden of chronic disease. Link:\u00a0 https:\/\/doi.org\/10.1503\/cmaj.170292<\/p>\n","protected":false},"author":1,"featured_media":2441,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_eb_attr":"","_lmt_disableupdate":"","_lmt_disable":"","footnotes":"","_wpscppro_dont_share_socialmedia":false,"_wpscppro_custom_social_share_image":0,"_facebook_share_type":"","_twitter_share_type":"","_linkedin_share_type":"","_pinterest_share_type":"","_linkedin_share_type_page":"","_instagram_share_type":"","_medium_share_type":"","_threads_share_type":"","_selected_social_profile":[],"_wpsp_enable_custom_social_template":false,"_wpsp_social_scheduling":{"enabled":false,"datetime":null,"platforms":[],"status":"template_only","dateOption":"today","timeOption":"now","customDays":"","customHours":"","customDate":"","customTime":"","schedulingType":"absolute"},"_wpsp_active_default_template":true},"categories":[4],"tags":[],"class_list":["post-2439","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publications"],"acf":[],"modified_by":"pathwp","_links":{"self":[{"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/posts\/2439","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/comments?post=2439"}],"version-history":[{"count":2,"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/posts\/2439\/revisions"}],"predecessor-version":[{"id":2534,"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/posts\/2439\/revisions\/2534"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/media\/2441"}],"wp:attachment":[{"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/media?parent=2439"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/categories?post=2439"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.atlanticpath.ca\/index.php\/wp-json\/wp\/v2\/tags?post=2439"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}