Tag: Genomics

Upcoming Webinar – CanPath’s Genomic Landscape

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Webinar: CanPath’s genomic data landscape: Insights from Ontario and Quebec Canada’s largest genomic data resource just got bigger … how will you use it? ?? CanPath now offers even more genotyping data from the Ontario Health Study (OHS) and CARTaGENE (Quebec), creating new opportunities to explore genetic ancestry, disease risk, and innovative research approaches. Join Dr. Philip Awadalla and Dr. Guillaume Lettre on Tuesday, March 2, at 11:00 AM EDT as they describe: Ontario’s latest genotyping data & research applications Genetic ancestry, the French Canadian founder effect & whole genome sequencing Emerging tools like liquid biopsy, cell-free DNA & single-cell studies Registration: https://bit.ly/41mOPq1

Webinar: Genomic and environmental influences on Canadian health phenotypes and chronic disease outcomes

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Webinar: Genomic and environmental influences on Canadian health phenotypes and chronic disease outcomes When? July 18, 2024, 2pmEST/3pmAST Register: https://bit.ly/3XU9Jws In this talk, Drs. Philip Awadalla and Marie-Julie Favé describe the intricate interplay between genetic and environmental factors and their influence on chronic diseases and phenotypes, utilizing data from CanPath, Canada’s largest population health cohort. By integrating genomic, environmental, and lifestyle data, Drs. Awadalla and Favé uncover how gene-environment interactions shape health outcomes. These findings provide insights into disease mechanisms and potential interventions, highlighting the importance of large and deep population cohort data. Attendees will gain a deeper understanding of the complex dynamics that contribute to chronic disease development and the critical role of comprehensive population health studies in identifying at-risk populations and individuals, supporting both personalized and public health strategies.  

CanPath transforming data access to unlock its full potential to improve health

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“New funding from Genome Canada will help CanPath build a cloud-based platform to equip researchers to understand the drivers of health and disease in Canada. Inside an unprecedented collection of health data from more than 330,000 Canadians are clues to understanding why people develop disease and how to prevent it. And a new project to improve how researchers access that data could lead to a future where Canadians get better, more personalized treatments for diseases like cancer.” CanPath is the “country’s largest population health study. Bringing together data from seven regional cohorts across 10 provinces, CanPath is a tremendous scientific resource of health, genomic and other data from about one in 100 Canadians. Now, CanPath is set to transform how it shares this data with researchers. Thanks to a $6.2 million grant from Genome Canada, CanPath is building a ‘trusted research environment,’ a secure cloud-based platform where researchers can access and analyze data all in one place.” ““This has the potential to be a game changer, both for CanPath’s long-term sustainability and the future of health research and healthcare in Canada,” says Dr. John McLaughlin, CanPath’s Executive Director and Professor of Epidemiology at the University of Toronto.” Full press release from the Ontario Institute for Cancer Research: https://oicr.on.ca/canpath-transforming-data-access-to-unlock-its-full-potential-to-improve-health/

Genome BC’s Annual Genomics Forum – May 3, 2023

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CanPath National Scientific Director, Dr. Philip Awadalla and BC Generations Scientific Director, Dr. Parveen Bhatti will be speaking in session 4, “All In: Using Large Population-Based Genomics Studies to Inform Patient Care.”  Wednesday, May 3rd: 3:00-4:30pm PST / 6:00-7:30EST / 7:00-8:30pmAST Registration: https://events.genomebc.ca/genomics-forum-2023/ Session Description: “Large population-based studies have taken place in several countries. Examples include All of Us (USA), 100,000 Genomes Project (UK) and Australian Genomics. This session will explore how these countries have made their project successful and how Canada can leverage already existing data and samples to have its own large cohort initiative — one that supports the development of disease screening, diagnostic, prevention and treatment, as well as inform public health policies for our diverse population.” Speakers: Zsuzsanna Hollander (Moderator) – Genome British Columbia Philip Awadalla (Presenter) – CanPath (Canadian Partnership for Tomorrow’s Health) Parveen Bhatti (Presenter) – BC Cancer Research Institute Anastasia Wise – All of Us Research Program, National Institutes of Health Tiffany Boughtwood – Australian Genomics About the Event: “Precision health care promises to target the right treatments to the right patients at the right time. And while genomics technologies have been used to effectively treat patients in health research for decades, thereby revolutionizing patient care, there are areas where these transformational technologies have not yet had a major impact. Join Genome BC on May 3, 2023, this year’s Annual Genomics Forum as we discuss the power and hurdles of integrating genomics into patient management and how we can ensure maximum value is derived from samples and patient data. Other countries have been leading the way in translational genomics research through initiatives such as “All of Us”, inviting one million people across the United States to help build one of the most diverse health databases in history. Australia Genomics has established a national collaboration supporting the translation of genomic research into clinical practice. And Genomics England’s initiative to sequence 100,000 genomes of patients affected by rare diseases or cancer is providing groundbreaking insights and continued findings into the role genomics can play in health care. Though efforts such as these have yet to materialize in Canada, can we leverage already existing biobanks and health data administration systems to make gains and fulfil the promise of precision health for Canadians? Let us learn how we can individually and collectively contribute to filling this gap while ensuring that research and health care advances are equitable to all.” https://events.genomebc.ca/genomics-forum-2023/

Funding Announcement — Enabling Personalized Genomics in Health with the CanPath Data Safe Haven

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Congratulations to CanPath as one of the new Genome Canada supported projects! “The Honourable François-Philippe Champagne, Minister of Innovation, Science and Industry, announced $18.1 million in federal support through Genome Canada for 13 late-stage research and development projects tackling major challenges in health, environment and agriculture through genomics. The projects announced today—deployed through diverse research partnerships with industry, healthcare organizations, as well as provincial and other federal partners—will harness cutting-edge genomics science to deliver real world impacts for healthier, more sustainable and prosperous communities across Canada. These public-private partnerships will generate solutions for: Health, by delivering life-saving precision health, new treatment and diagnosis options, and public health innovation for pathogen surveillance. Environmental sustainability, by driving environmental protection in mining and development of new tools to ensure ecosystem health. Resilient agriculture, by enabling nature-based solutions for pest management.” Additional Details: https://genomecanada.ca/genome-canada-investments-drive-cutting-edge-rd-in-health-environmental-sustainability-and-agricultural-resilience/ CanPath, in partnership with Ontario Genomics, will focus on Enabling Personalized Genomics in Health with the CanPath Data Safe Haven. Led by Dr. Philip Awadalla (co-Scientific Director, CanPath), Dr. John McLaughlin (Executive Director, CanPath) and Dr. Trevor Dummer (co-Scientific Director, CanPath). “Personalized healthcare programs require the collection and integration of high-quality data and biosamples from a vast number of individuals to capture the complex factors that can shape an individual’s health over the course of their lifetime. To enable discovery, evidence generation and policy change, the data must be accessible to both researchers, as well as public and commercial health decision makers. In Canada, the sharing and combining of data across jurisdictions, rather than collecting the data itself, is a major barrier to progress in precision medicine. The promise of personalized medicine is within reach through the Canadian Partnership for Tomorrow’s Health project (CanPath): Canada’s largest population health cohort. CanPath has made major strides towards integrating clinical, environmental, and population-level health data across all provinces and providing a national access point to deeply characterized and longitudinal health and lifestyle information, more so than any other entity in Canada. Here, the team will build upon CanPath’s existing national infrastructure to democratize access to the CanPath platform to better enable Canadian-led innovation and discovery. They will develop and pilot a data safe haven (DSH), a secure environment within which researchers, clinicians and industry in Canada can access deeply characterized population health and biobank data. In partnership with Adela, they will generate genomic data that will be hosted alongside clinical and population data of consented CanPath participants from across Canada within this secure digital framework. The DSH holds the potential to launch Canada to the forefront of genomic medicine globally. It will also support the development of Canada’s biotechnology sector and industry research as well as creating the ability to harmonize with leading precision medicine programs. The ultimate result will be earlier diagnosis of disease, advances in medical interventions, and improved health system performance for Canadians.” https://bit.ly/43JPW3q