Month: November 2023

Dr. Philip Awadalla represents CanPath at #CCRC2023

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CanPath Scientific Director, Dr. Philip Awadalla, will represent CanPath at the Canadian Cancer Research Conference. Dr. Awadalla is also the Director of Computational Biology and Senior Investigator at the Ontario Institute for Cancer Research, Professor of Population and Medical Genomics at the University of Toronto, and Executive Director of the Ontario Health Study. His research interests include the development of genomics approaches, model-based tools, and population-based approaches to study mutation rates, genome biology, and cancer.   Along with Patient Partner and Atlantic PATH participant, Pauline McIntyre, Dr. Awadalla will chair a panel on CanPath: Canada’s Largest Population Laboratory for Cancer Research on Monday, November 13th at 11:40 AST. Presenters include    Dr. Dylan O’Sullivan (Alberta Health Services, University of Calgary) speaking about risk factors for early-onset colorectal cancer;  Dr. Samina Abidi (Dalhousie University) speaking about a digital health and artificial-based public health platform for cancer risk prediction;  Dr. Sara Nejatinamini (Alberta Tomorrow Project, Alberta Health Services) speaking about changes in breast and cervical cancer screening during the COVID-19 pandemic; and   Dr. Vikki Ho (University of Montreal, CARTaGENE) speaking about harnessing data to build a cancer prevention research program.  Dr. Awadalla will also represent CanPath on a panel chaired by Dr. Sherri Christian on Networked Cancer Research in Canada on Tuesday, November 14th at 9:00am AST.   

Evidence that ovarian hormones, but not diet and exercise, contribute to the sex disparity in post-traumatic stress disorder

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Authors: Megan Wiseman, Megan Hinks, Darcy Hallett, Jaqueline Blundell, Ellen Sweeney, Christina Thorpe, Susan Walling, Ashlyn Swift-Gallant Journal: Journal of Psychiatric Research, 168. Abstract: Females are twice as likely as males to receive a diagnosis of post-traumatic stress disorder (PTSD). One hypothesis for this sex disparity is that ovarian hormones, including estrogen and progesterone, contribute to PTSD risk. Alternatively, sex differences in lifestyle factors, such as diet and exercise, may play a role in PTSD risk. Using data from the Atlantic Partnership for Tomorrow’s Health (PATH) cohort (n = 16,899), the relationship between endogenous hormone fluctuations (e.g., menarche, pregnancy, and menopause), exogenous hormone use (e.g., hormonal contraception and hormone replacement therapy (HRT)) and lifestyle variables (diet and exercise habits, as measured by the Mediterranean Diet Adherence Screener, Healthy Eating Index, and International Physical Activity Questionnaire) with PTSD diagnosis and treatment were analyzed. While several hormonal variables, including contraceptive use, higher total number of pregnancies, younger menarche age, and having undergone menopause increased the risk of PTSD, no lifestyle variables contributed to an increased risk of PTSD diagnosis. These findings support the theory that ovarian hormones contribute to the sex-linked disparity in PTSD diagnosis. doi: https://doi.org/10.1016/j.jpsychires.2023.10.048

New Publication – PTSD and Ovarian Hormones

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Congratulations to Dr. Ashlyn Swift-Gallant and team on their new publication in the Journal of Psychiatric Research, “Evidence that ovarian hormones, but not diet and exercise, contribute to the sex disparity in post-traumatic stress disorder.” Dr. Swift-Gallant’s research used questionnaire data from Atlantic PATH participants. Free 50 day access: https://bit.ly/46SNDft Dr. Swift-Gallant is based in the Department of Psychology at Memorial University in Newfoundland and Labrador. Their research examines the role hormones play in the development of the brain and behaviour with the overall goal of understanding how individual differences develop.

Canadian Cancer Research Conference Community Event

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CanPath and Atlantic PATH are excited to participate in the upcoming Community Event, “Cancer: Prevention, Treatment & You” at the Canadian Cancer Research Conference. Our team members are looking forward to meeting you!   Megan Fleming, Communications and Knowledge Translation Officer, CanPath  Jason Hicks, Executive Director, Atlantic PATH   Ellen Sweeney, Research Director, Atlantic PATH  This free event is open to the public:  Explore an exhibit hall with resources for people of all ages  Speak one-on-one with patient advocates  Learn about risk reduction  Get up-to-date information on screening and treatment, as well as helpful advice on life after a cancer diagnosis   Panel: Moderated by Eilish Bonang, Anchor of Global Morning News in Halifax, you will hear about interesting research from:  Dr. Nathalie Saint-Jacques, MSc, PhD, Senior Epidemiologist, Nova Scotia Health Cancer Care Program  Dr Michael N. Ha, MD, PhD, FRCPC, Radiation Oncologist, Nova Scotia Health  Mr. Tom Christensen, MSc, Clinical Exercise Physiologist (CSEP-CEP), Physical Activity and Cancer (PAC) Lab   Details:   Saturday, November 11th   1:30-4:30pm AST  Halifax Convention Centre: Argyle Suite  1650 Argyle Street, Halifax 

CanPath and Regional Cohorts at the Canadian Cancer Research Conference (#CCRC2023)

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CanPath and its regional cohorts will be well represented at the upcoming Canadian Cancer Research Conference in Halifax on November 11-14th. This conference is hosted by the Canadian Cancer Research Alliance. It brings together the Canadian cancer research community and spans the research spectrum.   We’re pleased to have attendees from the CanPath National Coordinating Centre and regional cohorts including Atlantic PATH, CARTaGENE (Quebec), the Ontario Health Study, the Manitoba Tomorrow Project, Alberta’s Tomorrow Project, and the BC Generations Project.   Over the next two weeks, we will share more details about where to find CanPath and regional cohort representatives at the conference (e.g., plenaries, concurrent and lightning sessions, poster presentations, etc.), as well as researchers who have used data and biological samples from CanPath and the regional cohorts. Stay tuned!