Depression, Anxiety, and the Risk of Cancer: An Individual Participant Data Meta-Analysis

Authors: LonnekeA. van Tuijl, Maartje Basten, Kuan‐Yu Pan, Roel Vermeulen, Lützen Portengen, Alexander de Graeff, Joost Dekker, Mirjam I. Geerlings, Adriaan Hoogendoorn, Femke Lamers, Adri C. Voogd, Jessica Abell, Philip Awadalla, Aartjan T.F. Beekman, Ottar Bjerkeset, Andy Boyd, |Yunsong Cui, Philipp Frank, Henrike Galenkamp, Bert Garssen, Sean Hellingman, Martijn Huisman, Anke Huss, Trynke R. de Jong, Read more about Depression, Anxiety, and the Risk of Cancer: An Individual Participant Data Meta-Analysis[…]

Assessing Skin Cancer Risk Factors, Sun Safety Behaviors and Melanoma Concern in Atlantic Canada: A Comprehensive Survey Study

Authors: François Lagacé, Bibi Nuzha Noorah, Santina Conte, Lorena Alexandra Mija, Jasmine Chang, Leila Cattelan, Jonathan LeBeau, Joël Claveau, Irina Turchin, Wayne Gulliver, Robert Gniadecki, Elena Netchiporouk, Wilson H. Miller Jr., Thomas G. Salopek, Elham Rahme, Sandra Peláez, and Ivan V. Litvinov. Journal: Cancers Abstract Background: The incidence of cutaneous melanoma (CM) is increasing at an alarming rate in Canada and elsewhere around the world. Significant regional differences Read more about Assessing Skin Cancer Risk Factors, Sun Safety Behaviors and Melanoma Concern in Atlantic Canada: A Comprehensive Survey Study[…]

Toenail arsenic species and metallome profiles associated with breast, cervical, prostate, and skin cancer prevalence in the Atlantic Partnership for Tomorrow’s Health cohort

Authors: Kalli Hood, Ellen Sweeney, Gabriela Ilie, Erin Keltie, Jong Sung Kim Journal: Frontiers in Public Health, Sec. Environmental Health and Exposome Abstract: Introduction: Chronic exposure to arsenic through drinking water has been linked to several cancers. The metabolism of arsenic is thought to play a key role in arsenic-related carcinogenesis as metabolites of varying toxicity Read more about Toenail arsenic species and metallome profiles associated with breast, cervical, prostate, and skin cancer prevalence in the Atlantic Partnership for Tomorrow’s Health cohort[…]

Investigating the Oral Microbiome in Retrospective and Prospective Cases of Prostate, Colon and Breast Cancer

Authors: Jacob Nearing, Vanessa DeClercq, Morgan Langille Journal: Nature Biofilms and Microbiomes Abstract: The human microbiome has been proposed as a potentially useful biomarker for several cancers. To examine this, we made use of salivary samples from the Atlantic Partnership for Tomorrow’s Health (PATH) project and Alberta’s Tomorrow Project (ATP). Sample selection was divided into both Read more about Investigating the Oral Microbiome in Retrospective and Prospective Cases of Prostate, Colon and Breast Cancer[…]

Applying Machine Learning to Arsenic Species and Metallomics Profiles of Toenails to Evaluate Associations of Environmental Arsenic with Incident Cancer Cases

Authors: Sheida Majouni, Jong Sung Kim, Ellen Sweeney, Erin Keltie, Syed Sibte Raza Abidi Ebook: Volume 294: Challenges of Trustable AI and Added-Value on Health Abstract: Chronic exposure to environmental arsenic has been linked to a number of human diseases affecting multiple organ systems, including cancer. The greatest concern for chronic exposure to arsenic is Read more about Applying Machine Learning to Arsenic Species and Metallomics Profiles of Toenails to Evaluate Associations of Environmental Arsenic with Incident Cancer Cases[…]

Arsenic Speciation and Metallomics Profiling of Human Toenails as a Biomarker to Assess Prostate Cancer Cases: Atlantic PATH Cohort Study

Authors: Erin Keltie, Kalli Hood, Yunsong Cui, Ellen Sweeney, Gabriela Ilie, Anil Adisesh, Trevor Dummer, Veni Bharti, Jong Sung Kim Journal: Frontiers in Public Health (Environmental Health and Exposome) Abstract: Chronic exposure to inorganic arsenic and trace metals has been linked to prostate cancer, and altered arsenic methylation capacity may have an important role in Read more about Arsenic Speciation and Metallomics Profiling of Human Toenails as a Biomarker to Assess Prostate Cancer Cases: Atlantic PATH Cohort Study[…]

Substituting bouts of sedentary behavior with physical activity: Adopting positive lifestyle choices in people with a history of cancer

Authors: Lee Ingle, Samantha Ruilova, Yunsong Cui, Vanessa DeClercq, Ellen Sweeney, Zhijie Michael Yu, Cynthia C. Forbes Journal: Cancer Causes and Control Abstract Purpose To determine in people with a history of cancer, whether substituting sitting time with other daily activities (i.e., sleeping, walking, moderate and vigorous physical activity) was associated with changes in waist Read more about Substituting bouts of sedentary behavior with physical activity: Adopting positive lifestyle choices in people with a history of cancer[…]

Lifestyle factors and lung cancer risk among never smokers in the Canadian Partnership for Tomorrow’s Health (CanPath)

Journal: Cancer Causes and Control Authors: Rachel A. Murphy,  Maryam Darvishian, Jia Qi, Yixian Chen, Quincy Chu, Jennifer Vena, Trevor J. B. Dummer, Nhu Le, Ellen Sweeney, Vanessa DeClercq, Scott A. Grandy, Melanie R. Keats, Yunsong Cui, Philip Awadalla, Darren R. Brenner & Parveen Bhatti   Abstract Background Although smoking is the primary risk factor for lung cancer, 15–25% of lung cancers occur in never smokers. Emerging evidence suggests lifestyle Read more about Lifestyle factors and lung cancer risk among never smokers in the Canadian Partnership for Tomorrow’s Health (CanPath)[…]

Investigation of the impact of commonly used medications on the oral microbiome of individuals living without major chronic conditions

Authors: Vanessa DeClercq, Jacob T. Nearing, and Morgan G.I. Langille Journal: PLOS One Abstract Background: Commonly used medications produce changes in the gut microbiota, however, the impact of these medications on the composition of the oral microbiota is understudied. Methods: Saliva samples were obtained from 846 females and 368 males aged 35-69 years from a Canadian population Read more about Investigation of the impact of commonly used medications on the oral microbiome of individuals living without major chronic conditions[…]

Analysis of human serum and urine for tentative identification of potentially carcinogenic pesticide-associated N-nitroso compounds using high-resolution mass spectrometry

Journal: Environmental Research Authors: Crystal L. Sweeney, Nathan K. Smith, Ellen Sweeney, Alejandro M. Cohen, and Jong Sung Kim Abstract: Human serum and urine samples were analyzed for a suite of nitrosatable pesticides and potentially carcinogenic pesticide-associated N–nitroso (PANN) compounds. Formation of PANN compounds may occur in vivo after consumption of food or water containing trace amounts of Read more about Analysis of human serum and urine for tentative identification of potentially carcinogenic pesticide-associated N-nitroso compounds using high-resolution mass spectrometry[…]