Investigation of the impact of commonly used medications on the oral microbiome of individuals living without major chronic conditions

Authors: Vanessa DeClercq, Jacob T. Nearing, and Morgan G.I. Langille Journal: PLOS One Abstract Background: Commonly used medications produce changes in the gut microbiota, however, the impact of these medications on the composition of the oral microbiota is understudied. Methods: Saliva samples were obtained from 846 females and 368 males aged 35-69 years from a Canadian population Read more about Investigation of the impact of commonly used medications on the oral microbiome of individuals living without major chronic conditions[…]

Analysis of human serum and urine for tentative identification of potentially carcinogenic pesticide-associated N-nitroso compounds using high-resolution mass spectrometry

Journal: Environmental Research Authors: Crystal L. Sweeney, Nathan K. Smith, Ellen Sweeney, Alejandro M. Cohen, and Jong Sung Kim Abstract: Human serum and urine samples were analyzed for a suite of nitrosatable pesticides and potentially carcinogenic pesticide-associated N–nitroso (PANN) compounds. Formation of PANN compounds may occur in vivo after consumption of food or water containing trace amounts of Read more about Analysis of human serum and urine for tentative identification of potentially carcinogenic pesticide-associated N-nitroso compounds using high-resolution mass spectrometry[…]

The Impact of Reporting Magnetic Resonance Imaging Incidental Findings in the Canadian Alliance for Healthy Hearts and Minds Cohort

Journal: BMC Medical Ethics Authors: Judy M. Luu, Anand K. Sergeant, Sonia S. Anand, Dipika Desai, Karleen Schulze, Bartha M. Knoppers, Ma’n H. Zawati, Eric E. Smith, Alan R. Moody, Sandra E. Black, Eric Larose, Francois Marcotte, Erika Kleiderman, Jean-Claude Tardif, Douglas S. Lee, Matthias G. Friedrich on behalf of the CAHHM Study Investigators Abstract Read more about The Impact of Reporting Magnetic Resonance Imaging Incidental Findings in the Canadian Alliance for Healthy Hearts and Minds Cohort[…]

Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses

Journal: Brain and Behavior Authors: Lonneke A. van Tuijl, Adri C. Voogd, Alexander de Graeff, Adriaan W. Hoogendoorn, Adelita V. Ranchor, Kuan-Yu Pan, Maartje Basten, Femke Lamers, Mirjam I. Geerlings, Jessica G. Abell, Philip Awadalla, Marije F. Bakker, Aartjan T.F. Beekman, Ottar Bjerkeset, Andy Boyd, Yunsong Cui, Henrike Galenkamp, Bert Garssen, Sean Hellingman, Martijn Huisman, Read more about Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses[…]

Post-Treatment Adverse Health Correlates among Prostate Cancer Survivors in a Sample of Men Residing in Atlantic Canada

Title: Post-Treatment Adverse Health Correlates among Prostate Cancer Survivors in a Sample of Men Residing in Atlantic Canada Journal: Current Oncology Authors: Gabriela Ilie, Rob Rutledge and Ellen Sweeney Abstract: Background: Recent large population-based studies have shed light on an association between prostate cancer (PCa) survivorship and mental health, which emerged when the comparison group Read more about Post-Treatment Adverse Health Correlates among Prostate Cancer Survivors in a Sample of Men Residing in Atlantic Canada[…]

Environmental Correlates of Physical Activity, Sedentary Behavior, and Self-Rated Health in Chronic Obstructive Pulmonary Disease

Journal: Journal of Cardiopulmonary Rehabilitation and Prevention Authors: Daniel Stevens, Pantelis Andreou, Daniel Rainham Abstract : Purpose: Physical activity (PA) predicts important health outcomes in chronic obstructive pulmonary disease (COPD). In the general population, environmental factors have the potential to influence PA; however, data are limited in this clinical population. Therefore, we sought to investigate associations Read more about Environmental Correlates of Physical Activity, Sedentary Behavior, and Self-Rated Health in Chronic Obstructive Pulmonary Disease[…]

Age and Sex-Specific Associations in Health Risk Factors for Chronic Disease: Evidence from the Atlantic Partnership for Tomorrow’s Health (PATH) Cohort

Title: Age and Sex-Specific Associations in Health Risk Factors for Chronic Disease: Evidence from the Atlantic Partnership for Tomorrow’s Health (PATH) Cohort Journal: Canadian Journal on Aging Authors: Vanessa DeClercq and Ellen Sweeney Abstract: The objective of this study was to discern health risk factors for chronic disease by age and sex in a Canadian Read more about Age and Sex-Specific Associations in Health Risk Factors for Chronic Disease: Evidence from the Atlantic Partnership for Tomorrow’s Health (PATH) Cohort[…]

The association between mental health and shift work: Findings from the Atlantic PATH study

Journal: Preventive Medicine Authors: Ellen Sweeney, Yunsong Cui, Zhijie Michael Yu, Trevor JB Dummer, Vanessa DeClercq, Cynthia Forbes, Scott A Grandy, Melanie R Keats, Anil Adisesh Abstract We evaluated the relationship between mental health and shift work in the Atlantic Partnership for Tomorrow’s Health (PATH) cohort study. In a matched study with 12,413 participants, including Read more about The association between mental health and shift work: Findings from the Atlantic PATH study[…]

Diabetes, Brain Infarcts, Cognition, and Small Vessels in the Canadian Alliance for Healthy Hearts and Minds Study

Journal: The Journal of Clinical Endocrinology & Metabolism Authors: Hertzel C Gerstein, Eric E Smith, Chinthanie Ramasundarahettige, Dipika Desai, Philip Awadalla, Philippe Broet, Sandra Black, Trevor J B Dummer, Jason Hicks, Alan Moody, Jean-Claude Tardif, Koon K Teo, Jennifer Vena, Salim Yusuf, Douglas S Lee, Matthias G Friedrich, Sonia S Anand Abstract: Background Diabetes is a risk factor for cerebrovascular disease and cognitive impairment. The anatomical basis for this is uncertain. Read more about Diabetes, Brain Infarcts, Cognition, and Small Vessels in the Canadian Alliance for Healthy Hearts and Minds Study[…]

Regional Comparisons of Associations Between Physical Activity Levels and Cardiovascular Disease: The Story of Atlantic Canada

Journal: Canadian Journal of Cardiology Authors: Bartosz Orzel, Melanie Keats, Yunsong Cui, Scott Grandy Abstract: Background Physical inactivity is an important risk factor for cardiovascular disease (CVD). Atlantic Canada is a region with lower physical activity (PA) levels and poorer CVD outcomes than the rest of Canada. Yet, within-region variation is expected. This study aimed Read more about Regional Comparisons of Associations Between Physical Activity Levels and Cardiovascular Disease: The Story of Atlantic Canada[…]