Oral microbial signatures associated with age and frailty in Canadian adults

Authors: Vanessa DeClercq, Robyn J. Wright, Jacob Nearing, and Morgan G.I. Langille Journal: Scientific Reports Abstract: This study aimed to assess the association between the oral microbiome, age, and frailty. Data and saliva samples were obtained from male and female participants aged 35–70 years (n = 1357). Saliva samples were analysed by 16S rRNA gene sequencing and differences in Read more about Oral microbial signatures associated with age and frailty in Canadian adults[…]

The mediating role of health behaviors in the association between depression, anxiety and cancer incidence: an individual participant data meta-analysis

Authors: Kuan-Yu Pan , Lonneke van Tuijl, Maartje Basten, Judith J. M. Rijnhart, Alexander de Graeff, Joost Dekker, Mirjam I. Geerlings, Adriaan Hoogendoorn, Adelita V. Ranchor, Roel Vermeulen, Lützen Portengen, Adri C. Voogd, Jessica Abell, Philip Awadalla, Aartjan T. F. Beekman, Ottar Bjerkese, Andy Boyd, Yunsong Cui, Philipp Frank, Henrike Galenkamp, Bert Garssen, Sean Hellingman, Monika Read more about The mediating role of health behaviors in the association between depression, anxiety and cancer incidence: an individual participant data meta-analysis[…]

Psychosocial factors, health behaviors and risk of cancer incidence: Testing interaction and effect modification in an individual participant data meta-analysis

Authors: Maartje Basten, Kuan-Yu Pan, Lonneke A. vanTuijl, Alexander deGraeff, Joost Dekker, Adriaan W.Hoogendoorn, Femke Lamers, Adelita V. Ranchor, Roel Vermeulen, Lützen Portengen, Adri C. Voogd, Jessica Abell, Philip Awadalla, Aartjan T.F. Beekman, Ottar Bjerkeset, Andy Boyd, Yunsong Cui, Philipp Frank, Henrike Galenkamp, Bert Garssen, Sean Hellingman, Martijn Huisman, Anke Huss, Melanie R. Keats, Almar A.L. Read more about Psychosocial factors, health behaviors and risk of cancer incidence: Testing interaction and effect modification in an individual participant data meta-analysis[…]

Evidence that ovarian hormones, but not diet and exercise, contribute to the sex disparity in post-traumatic stress disorder

Authors: Megan Wiseman, Megan Hinks, Darcy Hallett, Jaqueline Blundell, Ellen Sweeney, Christina Thorpe, Susan Walling, Ashlyn Swift-Gallant Journal: Journal of Psychiatric Research, 168. Abstract: Females are twice as likely as males to receive a diagnosis of post-traumatic stress disorder (PTSD). One hypothesis for this sex disparity is that ovarian hormones, including estrogen and progesterone, contribute to Read more about Evidence that ovarian hormones, but not diet and exercise, contribute to the sex disparity in post-traumatic stress disorder[…]

Depression, Anxiety, and the Risk of Cancer: An Individual Participant Data Meta-Analysis

Authors: LonnekeA. van Tuijl, Maartje Basten, Kuan‐Yu Pan, Roel Vermeulen, Lützen Portengen, Alexander de Graeff, Joost Dekker, Mirjam I. Geerlings, Adriaan Hoogendoorn, Femke Lamers, Adri C. Voogd, Jessica Abell, Philip Awadalla, Aartjan T.F. Beekman, Ottar Bjerkeset, Andy Boyd, |Yunsong Cui, Philipp Frank, Henrike Galenkamp, Bert Garssen, Sean Hellingman, Martijn Huisman, Anke Huss, Trynke R. de Jong, Read more about Depression, Anxiety, and the Risk of Cancer: An Individual Participant Data Meta-Analysis[…]

Assessing Skin Cancer Risk Factors, Sun Safety Behaviors and Melanoma Concern in Atlantic Canada: A Comprehensive Survey Study

Authors: François Lagacé, Bibi Nuzha Noorah, Santina Conte, Lorena Alexandra Mija, Jasmine Chang, Leila Cattelan, Jonathan LeBeau, Joël Claveau, Irina Turchin, Wayne Gulliver, Robert Gniadecki, Elena Netchiporouk, Wilson H. Miller Jr., Thomas G. Salopek, Elham Rahme, Sandra Peláez, and Ivan V. Litvinov. Journal: Cancers Abstract Background: The incidence of cutaneous melanoma (CM) is increasing at an alarming rate in Canada and elsewhere around the world. Significant regional differences Read more about Assessing Skin Cancer Risk Factors, Sun Safety Behaviors and Melanoma Concern in Atlantic Canada: A Comprehensive Survey Study[…]

Toenail arsenic species and metallome profiles associated with breast, cervical, prostate, and skin cancer prevalence in the Atlantic Partnership for Tomorrow’s Health cohort

Authors: Kalli Hood, Ellen Sweeney, Gabriela Ilie, Erin Keltie, Jong Sung Kim Journal: Frontiers in Public Health, Sec. Environmental Health and Exposome Abstract: Introduction: Chronic exposure to arsenic through drinking water has been linked to several cancers. The metabolism of arsenic is thought to play a key role in arsenic-related carcinogenesis as metabolites of varying toxicity Read more about Toenail arsenic species and metallome profiles associated with breast, cervical, prostate, and skin cancer prevalence in the Atlantic Partnership for Tomorrow’s Health cohort[…]

Investigating the Oral Microbiome in Retrospective and Prospective Cases of Prostate, Colon and Breast Cancer

Authors: Jacob Nearing, Vanessa DeClercq, Morgan Langille Journal: Nature Biofilms and Microbiomes Abstract: The human microbiome has been proposed as a potentially useful biomarker for several cancers. To examine this, we made use of salivary samples from the Atlantic Partnership for Tomorrow’s Health (PATH) project and Alberta’s Tomorrow Project (ATP). Sample selection was divided into both Read more about Investigating the Oral Microbiome in Retrospective and Prospective Cases of Prostate, Colon and Breast Cancer[…]

Applying Machine Learning to Arsenic Species and Metallomics Profiles of Toenails to Evaluate Associations of Environmental Arsenic with Incident Cancer Cases

Authors: Sheida Majouni, Jong Sung Kim, Ellen Sweeney, Erin Keltie, Syed Sibte Raza Abidi Ebook: Volume 294: Challenges of Trustable AI and Added-Value on Health Abstract: Chronic exposure to environmental arsenic has been linked to a number of human diseases affecting multiple organ systems, including cancer. The greatest concern for chronic exposure to arsenic is Read more about Applying Machine Learning to Arsenic Species and Metallomics Profiles of Toenails to Evaluate Associations of Environmental Arsenic with Incident Cancer Cases[…]

Harnessing the Power of Data Linkage to Enrich the Cancer Research Ecosystem in Canada

Authors: Robin Urquhart, Philip Awadalla, Parveen Bhatti, Trevor JB Dummer, Simon Gravel, Jennifer Vena, Riaz Alvi, Phillipe Broet, Cynthia Kendell, Victoria Kirsh, Guillaume Lettre, Kimberly Skead, Grace Shen-Tu, Ellen Sweeney, Donna Turner Journal: International Journal of Population Data Science Abstract: Objectives: We will enrich the cancer research ecosystem in Canada through linking cancer registry and Read more about Harnessing the Power of Data Linkage to Enrich the Cancer Research Ecosystem in Canada[…]