Atlantic PATH – Prostate Cancer Awareness Month

To round up Prostate Cancer Awareness Month, we are highlighting some of the recent and ongoing work on prostate cancer conducted using Atlantic PATH data and biosamples. Flashback to 2023 and welcoming our youngest team member(!) and the Plaid for Dad tradition raising awareness about prostate cancer in Canada. We have ongoing research on prostate cancer exploring environmental exposure to arsenic and cancer risk using toxicological and machine learning methods. This research stream has received and benefitted from funding from Nova Scotia Health, the Beatrice Hunter Cancer Research Institute, Prostate Cancer Canada, the Canadian Cancer Society, and the New Frontiers in Research Fund. Watch this space for new findings and publications! Related publications to date include: Majouni, S., Kim, J.S., Sweeney, E., Keltie, E., Abidi, S. (2022). Applying Machine Learning to Arsenic Species and Metallomics Profiles of Toenails to Evaluate Associations of Environmental Arsenic with Incident Cancer Cases. Medical Informatics Europe Conference (MIE) Conference Proceedings. Studies in Health Technology and Informatics. Keltie, E., Hood, K., Cui, Y., Sweeney, E., Ilie, G., Adisesh, A., Dummer, T.J.B., Bharti, V., Kim, J.S. (2022). Arsenic speciation and metallomics profiling of human toenails as a biomarker to assess prostate cancer cases: Atlantic PATH cohort study. Frontiers in Public Health, 10.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301242/ Hood, K., Sweeney, E., Ilie, G., Keltie, E., Kim, J.S. (2023). Toenail arsenic species and metallome profiles associated with breast, cervical, prostate, and skin cancer prevalence in the Atlantic Partnership for Tomorrow’s Health cohort. Frontiers in Public Health, Environmental Health and Exposome.  https://www.frontiersin.org/articles/10.3389/fpubh.2023.1148283/full Smith, N., Keltie, E., Sweeney, E., Weerasinghe, S., MacPherson, K., Kim, J.S. (2022). Toenail speciation biomarkers in arsenic-releated disease: a feasibility study for investigating the association between arsenic expsosure and chronic disease. Ecotoxicology and Environmental Safety, 232. https://www.sciencedirect.com/science/article/pii/S0147651322001099 The Langille Lab at Dalhousie University has an ongoing research stream on the microbiome. This work has included a focus on prostate cancer. Related publications include: Nearing, J., DeClercq, V., Langille, M. (2023). Investigating the Oral Microbiome in Retrospective and Prospective Cases of Prostate, Colon and Breast Cancer. Nature Biofilms and Microbiomes. https://www.nature.com/articles/s41522-023-00391-7. We have also conducted research on the mental health of prostate cancer survivors compared to those with no history of cancer and those with types of cancer. This work was supported by funding from the Beatrice Hunter Cancer Research Institute. Publications to date include: Ilie, G., Rutledge, R., Sweeney, E. (2020). Anxiety and depression symptoms in adult males in Atlantic Canada with or without a lifetime history of prostate cancer. Psycho-Oncology. https://onlinelibrary.wiley.com/doi/10.1002/pon.5244 Ilie, G., Rutledge, R., Sweeney, E. (2021). An examination of the role of socioeconomic status in the relationship between depression and prostate cancer survivorship in a population-based sample of men from Atlantic Canada. Oncology, 99(4). https://pubmed.ncbi.nlm.nih.gov/33486485/ Ilie, G., Rutledge, R., Sweeney, E. (2021). Post-Treatment Adverse Health Correlates among Prostate Cancer Survivors in a Sample of Men Residing in Atlantic Canada. Current Oncology, 28(4). https://www.mdpi.com/1718-7729/28/4/246

CanPath Round Up: Prostate Cancer Awareness Month

What could you uncover with data from over 3,500 participants with prostate cancer? 🤔💭 With close to 3,000 prevalent cases of prostate cancer within our participant population, CanPath remains committed to continuing to support participants and researchers in uncovering new breakthroughs in prostate cancer prevention, detection and treatment. By collecting biological, genetic and health data from our participants, we can keep track of new and existing cases of prostate cancer to provide researchers with access to invaluable health information to support the next generation of cancer research. 🔗 Get inspired by the latest prostate cancer publications using CanPath data: http://bit.ly/46VMeqJ

Government of Canada invests in research to strengthen pandemic preparedness and response

Read how CanPath, Canada’s largest health research study is ready to respond News release September 23, 2025 – Ottawa, Ontario – Canadian Institutes of Health Research “As we begin respiratory infectious diseases season, the Government of Canada is investing in critical research infrastructure to ensure that public health and immunization programs are as effective as they can be in protecting the health of Canadians and that Canada is ready for future pandemics and public health emergencies. Today, the Honourable Marjorie Michel, Minister of Health, announced an investment of nearly $20 million through the CIHR Centre for Research on Pandemic Preparedness and Health Emergencies and partners to support seven research platforms that unite researchers from all across the country to maintain Canada’s pandemic readiness, improve surveillance systems, and support evidence-based decision-making. These platforms will strengthen Canada’s capacity to detect, monitor, and respond to emerging infectious diseases, while addressing the social, behavioural, and health system challenges that arise during pandemics and other health emergencies. Broadly, the research teams will: These investments support the Government of Canada’s ongoing efforts to strengthen pandemic preparedness and protect the health of Canadians and the international community.” Quotes “The COVID-19 pandemic taught us the importance of being ready for the unexpected. These research investments will strengthen innovative science and collaboration across the country—helping Canada be better equipped to respond quickly and effectively to future public health emergencies.” —The Honourable Marjorie Michel, Minister of Health “These initiatives reflect the best of Canadian research, with a focus on real-world impact. Our scientists continue to provide the important evidence and maintain the research infrastructure that all Canadians rely on to prevent, prepare for, and respond to future health emergencies.” — Dr. Paul HĂ©bert, President, Canadian Institutes of Health Research Quick facts

CanPath awarded $3M to study crises in a changing world

Read the original news release from the Government of Canada Toronto, Canada, September 23, 2025 â€“ What if Canada had a research platform ready to track the next pandemic, study the effects of climate change on health, and help explain rising cancer rates in young people? With a $3 million grant from the Canadian Institutes of Health Research (CIHR), CanPath is that platform. Awarded through CIHR’s Pandemic Research Platforms Interim Funding opportunity, this two-year operating grant supports CanPath’s unique ability to generate fast, meaningful insights during public health emergencies. This work goes far beyond pandemics: it also aims to tackle broader crises like climate-related health risks and early-onset cancer. “This grant strengthens CanPath’s ability to respond quickly and effectively to future public health emergencies,” said Dr. Jennifer Brooks, CanPath’s Executive Director. “Our platform is built for this kind of work, with hundreds of thousands of Canadians already engaged, linked health records, and long-term follow-up in place.” The grant is led by Dr. Brooks and Dr. Philip Awadalla, CanPath’s National Scientific Co-Director, with a national team of co-investigators. The funding is held at the Dalla Lana School of Public Health, University of Toronto. “CanPath is known as a research resource, but now in its prime, it’s built for resilience,” said Dr. Awadalla. “We’re proud to continue this work with our partners and support Canada’s preparedness for emerging diseases in a changing world.” Canada’s largest health study is ready to respond CanPath, the Canadian Partnership for Tomorrow’s Health, is the country’s largest population health cohort, with more than 330,000 participants recruited from all 10 provinces. Participants have consented to long-term follow-up, data linkage, and future contact, providing a uniquely flexible and future-ready research platform. During the COVID-19 pandemic, CanPath rapidly deployed a national antibody study, linked testing data to participant records, and surveyed participants in real time. Results were shared widely with researchers, policymakers, and the public and featured by Global News, National Post, and The Globe and Mail. “CanPath’s COVID-19 response showed how powerful our model can be,” said Dr. Victoria Kirsh, CanPath National Scientific Coordinator. “We were able to launch surveys, test for antibodies, and communicate directly with participants in record time. This grant ensures we can build on that success, strengthen our partnerships, and stay ready to support evidence-based action when it matters most.” What this funding supports Through this grant, CanPath will continue to: This work builds on CanPath’s strategic partnerships with: Together, these partnerships strengthen CanPath’s role as a responsive, data-rich platform that serves researchers, funders, policymakers, and communities alike. Ready for the next challenge This grant builds on CanPath’s proven ability to act fast, scale up, and generate real-world impact. In future public health emergencies, CanPath is ready to: CanPath’s national team of investigators—including Drs. Trevor Dummer, Simon Gravel, Vikki Ho, Victoria Kirsh, Guillaume Lettre, Grace Shen-Tu, Jared Simpson, Ellen Sweeney, Megan Vanstone, Donna Turner, and Robin Urquhart—brings deep expertise across research fields and geographies. “This isn’t just about the next pandemic,” said Brooks. “It’s about being prepared for the full range of health challenges we’re facing, from chronic diseases—including cancer—to environmental change. This grant helps us keep Canada at the forefront of evidence-based, equitable research.” Pandemics don’t wait, and thanks to this investment, neither will CanPath. For more information, please contact:Megan FlemingCommunications & Knowledge Translation OfficerCanadian Partnership for Tomorrow’s Health (CanPath)info@canpath.ca

Arthritis Awareness Month

Please join Atlantic PATH in acknowledging Arthritis Awareness Month this September. Arthritis affects joints and other tissues which results in pain and limited mobility. One in five people in Canada live with arthritis and Atlantic Canada has some of the highest rates in the country. We would like to highlight arthritis research using data from Atlantic PATH participants. Dr. Cheryl Kozey and colleagues completed a study on the Current Management and Health Care Quality for Patients with Hip and Knee Osteoarthritis. The team used existing data from Atlantic PATH to examine self-reported characteristics of people living with and without osteoarthritis in all three Maritime Provinces (New Brunswick, Nova Scotia and Prince Edward Island).  The Atlantic PATH data for Nova Scotians was then linked to administrative data, accessed through Health Data Nova Scotia, in order to identify trends in health care use by Nova Scotians with and without osteoarthritis. The report, Current Management and Health Care Use for People with Osteoarthritis and infographic detail their findings, including that people with osteoarthritis in the Maritimes were older, more likely to be female, and had lower socioeconomic status compared to those without osteoarthritis. Participants with osteoarthritis from Atlantic PATH were invited to participate in an ancillary study. The article “Quality of Non-Surgical and Non-Pharmacological Knee Osteoarthritis Care in the Maritimes” highlights that more than half of individuals with mild-to-moderate knee osteoarthritis did not receive recommended core treatments in the Maritimes, highlighting a need to improve care for this patient group. Dr. Vanessa DeClercq‘s work focused on the relationship between adipokines and adiposity among females with rheumatoid and osteoarthritis. Using data and biological samples from Atlantic PATH, they found that those with higher levels of adiponectin were more likely to have osteoarthritis, but not rheumatoid arthritis. This study demonstrates differences in measures of adiposity and adipokines in specific types of arthritis.

Dr. Raza Abidi appointed Digital Health Canada Representative to IMIA

Join us in congratulating our colleague, Dr. Raza Abidi on being appointed Digital Health Canada Representative to the International Medical Informatics Association! Please see details below for the announcement. Dr. Abidi works alongside Dr. Jong Sung Kim and Dr. Ellen Sweeney on a longstanding research stream on environmental exposures and cancer using data and biological samples (toenails!) from Atlantic PATH. ***** Digital Health Canada’s Board of Directors is pleased to appoint Dr. Raza Abidi to the position of Digital Health Canada Representative to IMIA (the International Medical Informatics Association). Digital Health Canada has been the Canadian Representative since IMIA’s inception in 1980 and is a Charter member. Dr. Abidi is a tenured Professor at the Faculty of Computer Science, Dalhousie University, and holds a cross-appointment as Professor in the Dalhousie Department of Medicine. He is the founding director and lead scientist at the NICHE (kNowledge Intensive Computing in Healthcare Enterprises) research group that conducts interdisciplinary research at the intersection of digital health, artificial intelligence (AI) for healthcare, and digital transformation. Dr. Abidi served on the Digital Health Canada Board of Directors for six years and has a sound understanding of the mission and activities of the association. He is keenly aware of the need to bring the Canadian digital health community and its achievements to the world stage by enabling active participation in IMIA conferences, events, and working groups. Dr. Abidi is an internationally recognized healthcare researcher and leader with multiple international and national awards and recognitions. His primary research focus is Artificial Intelligence (AI) for healthcare and digital health, and he has extensive experience of (a) health data analytics using state-of-the-art AI methods to derive data-driven health intelligence, (b) health knowledge management by applying semantics-driven AI methods to derive knowledge-driven health intelligence by computerizing and operationalizing clinical practice guidelines/workflows, and (c) implementing research outputs as digital health solutions. His collaborative research activities have successfully led to (a) development of innovative point-of-care digital health solutions, (b) digital transformation of clinical workflows as decision support systems, (c) strategic planning and conception of new research themes and projects, (d) acquisition of multiple competitive research grants from various agencies and industry sponsors, (e) health data analysis and visualization, (f) health system evaluation and optimization studies, (g) publication of research articles at top-tier venues and invited talks, and (h) mentoring of junior researchers and talent development. I am confident that I can showcase the full potential of Canada in digital health research, innovation and entrepreneurship, and engage the broader Digital Health Canada community in IMIA activities so that Canada is regarded as a hub of digital health innovation and transformation. – Dr. Raza Abidi, Digital Health Canada Representative to the International Medical Informatics Association About IMIA IMIA provides leadership and expertise to the interdisciplinary health informatics community around the world. IMIA aims to enable the transformation of healthcare using information technology and plays a key role in promoting and furthering the application of digital technologies in healthcare. IMIA brings together leading scientists, researchers, vendors, developers, and consultants in a global context. Every two years, IMIA holds the preeminent international health informatics conference—World Congress on Medical and Health Informatics: MedInfo—where researchers and practitioners from around the world present their latest work in digital health. About this role As the new Digital Health Canada IMIA representative, Dr. Abidi will act as a liaison between Digital Health Canada and IMIA and will represent Canada on the world stage, connecting Digital Health Canada with representatives from corresponding national organizations and focusing on advances in digital health from other countries. Dr. Abidi will exercise voting rights on behalf of Digital Health Canada at the annual IMIA General Assembly, and will serve a two-year term on the IMIA Board as the Vice President North America.

Mental Health Week & Research

Unmasking mental health means asking deeper questions, and CanPath data is helping researchers find the answers. This Mental Health Week, we’re recognizing how interconnected mental health is with every part of life. Researchers are using Atlantic PATH data to explore: ? Mental health and shift work (Sweeney et al., 2021) ? Depression, anxiety and the risk of cancer incidence (van Tuijl et al., 2023) ? Socioeconomic status, depression and prostate cancer survivorship (Ilie et al., 2021) ? Post-treatment adverse health correlates among prostate cancer survivors (Ilie et al., 2021) ? Anxiety and depression in prostate cancer survivors (Ilie et al., 2020) Researchers are using CanPath data to explore: ? COVID-19 and mental health in 23 international cohorts (In progress) ? Depression, diet, and diabetes (Schmitz & Sen, 2024) ? System costs of effective mental healthcare coverage (Vasiliadis et al., 2024) ? And more, like how our environments and chronic diseases like cancer intersect with mental health When we look beyond the surface, we see the whole person, and more possibilities for care, policy, and prevention. ? Watch the webinar on depression, diet, and diabetes >> https://lnkd.in/eHNm97YM ? Read the latest publications addressing mental health using CanPath data >> https://lnkd.in/ecQkdGQR  

National Volunteer Week and Thank You Thursday

Happy National Volunteer Week and Thank You Thursday from CanPath and Atlantic PATH! Atlantic PATH participants are critical partners in advancing health research. For more than fifteen years, their voluntary contributions have enabled discoveries shaping the future of disease prevention, diagnosis, and care. Atlantic PATH participants’ commitment reminds us that every data point represents a person, and every discovery represents hope for healthier communities. Thank you to all our participants for making population health research possible. Learn more about participants’ impact, including Atlantic PATH participant, Barbara Campbell! https://canpath.ca/meet-canpath-participants/

New Article – The Association of Sleep Trouble and Physical Inactivity with Breast Cancer Risk in Nova Scotia

Congratulations to Dr. Cindy Feng on her new article, “The Association of Sleep Trouble and Physical Inactivity with Breast Cancer Risk in Nova Scotia: Evidence from the Atlantic PATH Cohort.” Breast cancer is a major public health concern, and modifiable health behaviors such as sleep quality and physical activity may influence risk. This study examined the associations between self-reported sleep trouble, sleep duration, and physical activity with breast cancer incidence in a prospective longitudinal cohort of 10,305 females from Nova Scotia. This work is part of Dr. Feng’s ongoing research with Atlantic PATH focused on predictive modeling and geographical analysis of cancer incidence in Atlantic Canada.  

New Article – Quality of Non-Surgical and Non-Pharmacological Knee Osteoarthritis Care in the Maritimes

Congratulations to Aleksandra Budarick, Dr. Cheryl Hubley-Kozey, Dr. Rebecca Moyer and team on their new article, “Quality of Non-Surgical and Non-Pharmacological Knee Osteoarthritis Care in the Maritimes.” Participants with osteoarthritis from Atlantic PATH were invited to participate in an ancillary study about the Current Management and Health Care Quality for Patients with Knee and Hip Osteoarthritis. Over half of individuals with mild-to-moderate knee osteoarthritis did not receive recommended core treatments in the Maritimes, highlighting a need to improve care for this patient group.