New Article – Investigating Skin Cancer Risk and Sun Safety Practices Among LGBTQ+ Communities in Canada

Congratulations to Dr. François Lagacé, Dr. Ivan Litvinov and team on their new article, “Investigating Skin Cancer Risk and Sun Safety Practices Among LGBTQ+ Communities in Canada.” Participants from Atlantic PATH and the Manitoba Tomorrow Project were invited to participate in the SunFit study led by Dr. Litvinov at McGill University. Skin cancer prevention requires effective sun safety practices. Previous studies have shown that LGBTQ+ individuals exhibit lower sunscreen use and higher tanning bed usage compared to their non-LGBTQ+ counterparts. This SunFit study is the first to assess skin cancer risk factors, sun-protective behaviors, and skin cancer concerns among LGBTQ+ participants across Canada.

Manitoba Representation at #CCRC2023 (Hrubeniuk, Briek, Katyal)

The Manitoba Tomorrow Project will be well represented at the Canadian Cancer Research Conference. Dr. Sachin Katyal is an Associate Professor at the University of Manitoba, Senior Scientist at CancerCare Manitoba Research Institute, and Director of the Manitoba Tumour Bank. Dr. Katyal is the Manitoba Tomorrow Project representative on the CanPath National Strategic Advisory Council. Dr. Katyal’s research interests include using advanced molecular, biochemical and genetic techniques to gain insight into the biology of mammalian DNA strand break repair pathways.  Dr. Katyal will be chairing a session on Clinical Innovations in the Real World with Patient Partner Ruth Ackerman on Monday, November 13th at 2:40pm AST. Speakers include   Dr. Tony Reiman (Beatrice Hunter Cancer Research Institute, Dalhousie University, University of New Brunswick) speaking about multiple myeloma and patient partners  Dr. Sheila Singh (Cancer Research Centre, McMaster University) speaking about clonal evolution in recurrent medulloblastoma  Dr. June Carroll (Faculty of Medicine, University of Toronto, Granovsky Gluskin Family Medicine Centre, Sinai Health) speaking about primary care strategies for hereditary cancer risk  Dr. Travis Hrubeniuk is the Project Lead at the Manitoba Tomorrow Project and an Assistant Professor at the Max Rady College of Medicine, Community Health Services, University of Manitoba. Dr. Hrubeniuk’s research interests focus on the relationships between, and the impact of various levels of physical activity, exercise, and sedentary behaviour on cancer and chronic disease throughout the lifespan and the subsequent influences on public health policy.  Dr. Hrubeniuk will be presenting a poster on the Manitoba Tomorrow Project as a cohort built for cancer research. Posters will be up for the duration of the conference and during viewing sessions on Sunday, November 12th from 12-1:30pm AST and Monday, November 13th from 1:10-2:40pm AST.  Noor Briek is a PhD candidate in the Department of Community Health Sciences at the University of Manitoba with an interest in population health and a primary focus on cancer epidemiology and pharmacoepidemiology. Noor is also a Research Assistant with the Manitoba Tomorrow Project and has rich practical experience as an international pharmacist since 2003 and a registered pharmacist (RPh) in Manitoba since 2010.  Noor will be presenting a virtual poster on their dissertation work linking drug data from the Manitoba Tomorrow Project Cohort and Administrative Health Databases: Advancing a Long-Term Health Research Platform for Cancer Research. Virtual posters will be accessible via the conference platform to all registered delegates via the virtual poster hall.  

CSEB Conference Update

The CanPath team was well represented at the Canadian Society for Epidemiology & Biostatistics (CSEB) Conference in Halifax on June 26-28, 2023. We had representatives from the CanPath National Coordinating Centre, Atlantic PATH, CARTaGENE, the Manitoba Tomorrow Project, and the Ontario Health Study that showcased the groundbreaking research and resources available related to epidemiology and biostatistics within CanPath and the regional cohorts. Throughout the conference, CanPath and the regional cohorts were well-represented in various sessions and discussions, particularly regarding data linkage. Some notable presentations included: ? Dr. Robin Urquhart, Scientific Director of Atlantic PATH, co-presented a workshop on data repositories in Canada ? Dr. Ellen Sweeney, Research Director of Atlantic PATH, presented at a concurrent session about research at Atlantic PATH exploring environmental exposure to arsenic and cancer risk using toxicological and machine-learning methods ? Dr. Vikki Ho, co-Scientific Director of CARTaGENE, co-presented a workshop on mentorship for junior faculty and funding opportunities ? Nicholas Cheng, PhD candidate at the Ontario Institute for Cancer Research, presented at a concurrent session about his research on leveraging population health cohorts to identify cancer biomarkers in blood up to seven years before diagnosis ? Poster sessions featured CanPath, the Manitoba Tomorrow Project, the Ontario Health Study, CARTaGENE, and more, showcasing the exceptional research happening at the regional level and how they can support epidemiological and biostatistical projects. Please connect with us to learn more about these projects. We are proud to contribute to advancing this critical field and look forward to continuing our efforts to drive positive health outcomes for all.                                   #CSEBConference2023 #Epidemiology #Biostatistics #EveryoneCounts #HealthResearch #Cohort #PopulationHealth

CanPath Representation at the Canadian Society for Epidemiology and Biostatistics Conference

We’re so glad to have representation from Atlantic PATH, CARTaGENE, Manitoba Tomorrow Project, Ontario Health Study, and CanPath at the Canadian Society for Epidemiology and Biostatistics Conference in Halifax this week! CanPath and the regional cohorts are well represented in the following sessions: Monday, June 26, 2023 Workshop 1 – Mentorship for Junior Faculty and Funding Opportunities: How to Break into the Game as a Junior Faculty Member [Dr. Vikki Ho, Scientific Co-Director, CARTaGENE] Workshop 3 – Data Repositories in Canada: Overview and Data Access 101  [Dr. Robin Urquhart, Scientific Director, Atlantic PATH] Tuesday, June 27, 2023 Concurrent Sessions B5: Lifecourse and Chronic Disease Epidemiology – Leveraging population health cohorts to identify cancer biomarkers in blood up to seven years prior to diagnosis          Presenter: Nicholas Chang, PhD candidate, OICR Poster Session   The Impact of Alcohol Consumption and Single Nucleode Polymorphisms on the High Rates of Colorectal Cancer in Atlantic Canada                                                                   Presenter: Carlee Feinstein, Research Assistant, St. FX                                                                                                                                                                                                        Authors: Carlee A Feinstein, Derrick G Lee, Allison Walsh, Tiffany S Bondo           The Manitoba Tomorrow Project: A Canadian Cohort Presented by: Dr. Travis Hrubeniuk, Project Lead, Manitoba Tomorrow Project Authors: Travis Hrubeniuk, Sachin Katyal, Donna Turner Canadian Partnership for Tomorrow’s Health (CanPath): Celebrang Compleng the Provincial Map and Cross-Province Data Linkage Presented by: Dr. John McLaughlin, Executive Director, CanPath Authors: John McLaughlin, Riaz Alvi, Philip Awadalla, Parveen Bhatti, Trevor Dummer, Jason Hicks, Vikki Ho, Grace Shen-Tu, Kimberly Skead, Ellen Sweeney, Donna Turner, Robin Urquhart, Jennifer Vena Examining the impact of inflammatory bowel disease on colorectal cancer risk in Atlantic Canada Presented by: Livia Clarke, Research Assistant, Dalhousie Medical School / St. FX Authors: Livia Clarke, Derrick Lee, Ellen Sweeney The Impact of Abnormal Sleep and Circadian Disruption on Atlantic Canada’s High Rate of Colorectal Cancer Presented by: Alison Walsh, Research Assistant, St. FX Authors: Alison J Walsh, Carlee A Feinstein, Tiffany S Bondoc, Megan K MacGillivray, Derrick G Lee The Ontario Health Study (OHS) Presented by: Sarah Salih, Data Analyst, Ontario Health Study Authors: Victoria Kirsh, Kimberly Skead, Kelly McDonald, Nancy Kreiger, Julian Lile, Karen Menard, John McLaughlin, Sutapa Mukherjee, Lyle Palmer, Vivek Goel, Mark Purdue, Sarah Salih, Philip Awadalla Smoking, aberrant DNA methylaon of the F2RL3 and AHRR genes, and lung cancer risk                                                                                                                                                     Presented by: Vikki Ho, Scientific Co-Director, CARTaGENE                                                                                                                                                                                                         Authors: Alice Nguyen, Anita Koushiki, Laura Pelland-St. Pierre, Michael Pham, Romain Pasquet, Sherryl Tauylor, Delphine Bosson-Rieutort, Vikki Ho The influence of occupaonal risk factors on DNA methylaon in the AHRR and F2RL3 genes Presented by: Laura Pelland-St-Pierre Authors: Michael Pham, Laura Pelland-St-Pierre, Alice Nguyen, Romain Pasquet, Sherryl Taylor, Delphine Bosson-Rieutort, Anita Koushik, Vikki Ho Wednesday, June 28, 2023 Concurrent Session C5: Cancer Epidemiology II – Exploring Environmental Exposure to Arsenic and Cancer Risk in the Atlantic PATH Cohort using Toxicological and Machine Learning Methods Presenter: Dr. Ellen Sweeney, Research Director, Atlantic PATH Please feel free to contact Atlantic PATH, CanPath or any of the regional cohorts to learn more about these projects!

Most CanPath study participants had infection-acquired antibodies but few suspected COVID-19

Dr. Victoria Kirsh presented at a CanPath webinar this week to present results from the SUPPORT-Canada study, funded by the federal COVID-19 Immunity Task Force (CITF). Data and blood spot samples were used from 22,300 participants from Atlantic PATH, CARTaGENE, the Ontario Health Study, Manitoba Tomorrow Project, Alberta’s Tomorrow Project, and BC Generations. Key findings include: 62% of participants had a COVID-19 infection based on anti-N measured antibody levels. Among those, 86% did not suspect they had ever had COVID-19. 95% of the COVID-19 infections were observed during the Omicron period. Risk of infection was increased among younger individuals, males, essential workers, and those who travelled. Participants with a reported COVID-19 infection reported symptoms from mild to severe, but few required hospitalization. The effectiveness of full or booster vaccination in preventing COVID-19 Omicron infection is short-term, only lasting 4 months. Time since last dose is a more important determinant of protection against infection than the number of doses. Antibody levels are correlates of vaccine-induced protection. Prior COVID-19 infection protects against reinfection for 8 months. The CanPath SUPPORT-Canada study has provided important findings related to the COVID-19 pandemic, vaccines and infections. With only 4 months of protection, these findings suggest that booster campaigns could be strategically used to rapidly boost immunity before upcoming waves of infection. Further, the longitudinal nature of CanPath participants ensures that we have a nationally representative population that can be followed for years to come (e.g., impact of Long COVID, future vaccinations, etc.). Link to recorded webinar: To come Link to webinar slide deck: https://www.covid19immunitytaskforce.ca/wp-content/uploads/2023/05/canpath-webinar-may-2023.pdf Link to CITF’s post: https://www.covid19immunitytaskforce.ca/most-canpath-study-participants-had-infection-acquired-antibodies-but-few-suspected-covid-19/